Experts Say Thimerosal Ban Would Imperil Global Health Efforts

A group of prominent doctors and public health experts warns in articles to be published Monday in the journal Pediatrics that banning thimerosal, a mercury compound used as a preservative in vaccines, would devastate public health efforts in developing countries.

Representatives from governments around the world will meet in Geneva next month in a session convened by the United Nations Environmental Program to prepare a global treaty to reduce health hazards by banning certain products and processes that release mercury into the environment.

But a proposal that the ban include thimerosal, which has been used since the 1930s to prevent bacterial and fungal contamination in multidose vials of vaccines, has drawn strong criticism from pediatricians.

They say that the ethyl-mercury compound is critical for vaccine use in the developing world, where multidose vials are a mainstay.

Banning it would require switching to single-dose vials for vaccines, which would cost far more and require new networks of cold storage facilities and additional capacity for waste disposal, the authors of the articles said.

“The result would be millions of people, predominantly in low- and middle-income countries, with significantly restricted access to lifesaving vaccines for many years,” they wrote.

In the United States, thimerosal has not been used in children’s vaccines since the early 2000s after the Food and Drug Administration and public health groups came under pressure from advocacy groups that believed there was an association between the compound and autism in children.

At the time, few, if any, studies had evaluated the compound’s safety, so the American Academy of Pediatrics called for its elimination in children’s vaccines, a recommendation that the authors argued was made under the principle of “do no harm.”

Since then, however, there has been a lot of research, and the evidence is overwhelming that thimerosal is not harmful, the authors said. Louis Z. Cooper, a former president of the academy and one of the authors, said that if the members had known then what they know now, they never would have recommended against using it. “Science clearly documented that we can’t find hazards from thimerosal in vaccines,” he said. “The preservative plays a critical role in distribution of vaccine to the global community. It was a no-brainer what our position needed to be.”

Advocacy groups have lobbied to include the substance in the ban, and some global health experts worry that because the government representatives due to vote next month are for the most part ministers of environment, not health, they may not appreciate the consequences of banning thimerosal in vaccines. The Pediatrics articles are timed to raise a warning before the meeting.

“If you don’t know about this, and you’re a minister of environment who doesn’t usually deal with health, it’s confusing,” said Heidi Larson, senior lecturer at the London School of Hygiene and Tropical Medicine, who runs the Vaccine Confidence Project.

In an open letter to the United Nations Environmental Program and the World Health Organization this year, the Coalition for Mercury-Free Drugs, a nonprofit group that supports the ban, disputed the assertion that scientific studies had offered proof that thimerosal is safe, and urged member states to include it in the ban.

That it is being used in developing countries, but not developed countries, is an “injustice,” the letter said.

The World Health Organization has also weighed in. In April, a group of experts on immunization wrote in a report that they were “gravely concerned that current global discussions may threaten access to thimerosal-containing vaccines without scientific justification.”

Dr. Larson said she believed that the efforts of pediatricians and global health experts, including the W.H.O., would influence the negotiations in Geneva and that the compound would most likely be left out of the final ban.

“You can’t just pull the plug on something without having a plan for an alternative,” she said.

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Diet Pepsi changing sweetener

Diet Pepsi is quietly changing its sweetener ahead of a major rebranding of the soft drink set for next month.

The change comes as PepsiCo Inc. looks to reinvigorate its namesake brands after losing market share to Coca-Cola Co. in recent years.

Cans of Diet Pepsi around the country now list a mix of two artificial sweeteners, a pairing that is commonly found in newer diet sodas. Previously, Diet Pepsi used only aspartame, which is sensitive to heat and breaks down more easily.

This summer, PepsiCo had declined to say whether it would go ahead with such a change after reports surfaced that it was testing the new sweeteners. Although the switch is intended only to help prevent the taste from degrading over time, companies are often sensitive to public perceptions that they might be tinkering with major brands. When reached for comment Sunday, PepsiCo spokeswoman Andrea Canabal said that Diet Pepsi with the new sweetener mix started hitting shelves in early December. She said the new mix will be more widely available in the coming weeks.

"It's not like a light switch. It'll start appearing as shelf space clears," she said. In January, the company is planning a major ad campaign, Canabal said, that will include a new logo with a heart and the theme "Love Every Sip."

The sweetener change will not be explicitly communicated in the ads.

In addition to aspartame, cans of Diet Pepsi found in New York, Omaha and the San Francisco Bay Area now list acesulfame potassium as an ingredient. The ingredient is often used in combination with other artificial sweeteners and can be found in a wide range of foods, including baked goods, chewing gum and gelatin desserts.

John Sicher, editor and publisher of industry tracker Beverage Digest, said the synergistic effect of mixing the two sweeteners is intended to help keep the drink's sweetening power at a constant level, making it taste fresh longer.

"A change in sweetener does not change the flavor," Sicher noted.

PepsiCo said in a statement Sunday that it was adding a "very small amount" of acesulfame potassium "to ensure consistency with every sip." The sweeteners used in Diet Pepsi vary depending on the region of the world.

The move to improve Diet Pepsi comes amid a broader push by PepsiCo to boost sales of its flagship soda. Under pressure from investors, Chief Executive Indra Nooyi this year announced that the company would step up investment in its flagship brands.

This year, PepsiCo has made several splashy moves, including a wide-ranging partnership with singer Beyonce and a multiyear deal with the National Football League to sponsor the Super Bowl halftime show. TV ads for Pepsi have also featured singer Nicki Minaj, New Orleans Saints quarterback Drew Brees, the boy band One Direction and international soccer stars, including Lionel Messi.

Whether the efforts will pay off with increased sales remains to be seen. In the latest quarter, PepsiCo said its soda volume in North America fell 2%, reflecting the broader decline in soft drink consumption that has plagued the industry since 1998. But the company noted that its share of the market had improved.

For now, Diet Pepsi remains the No. 7 carbonated soft drink with 4.9% of the market, according to Beverage Digest. That's down from 5.3% in 2000. Meanwhile, Diet Coke's share has increased in that time to 9.6% from 8.7%. Diet Coke, which still only uses aspartame, overtook regular Pepsi to become the No. 2 soda brand in 2010.

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In Connecticut, a mother coped silently with a troubled son

NEWTOWN, Conn. — On the outside, Nancy Lanza was the picture of contented motherhood: volunteering at her sons' school, gardening, keeping a picture-perfect home so well-ordered a neighbor described it as pristine.

Outside public view, say some who knew her, she had a struggle on her hands, and that was her son Adam: a brilliant but sometimes difficult boy.

Lanza battled with the school district over Adam and eventually quit her job, pulled him out of school and educated him at home, said her sister-in-law, Marsha Lanza.

"I know she had issues with the school. … In what capacity, I'm not 100% certain if it was behavior, if it was learning disabilities, I really don't know," Marsha Lanza told reporters. The investigation widened Saturday into the still-baffling shootings at Sandy Hook Elementary School in Newtown, Conn., with police releasing the identities of the 26 students and teachers they say Adam Lanza shot before turning the gun on himself.

His mother, police said, was shot at the family home before her son set out on his deadly rampage through the school.

"Adam, he was … definitely the challenge to the family in that house," Marsha Lanza said. "Every family has one. I have one. They have one. … But he was a very bright boy, he was smart."

Jim Leff, who knew Nancy Lanza casually through a friend, said he had been put off by an impression that she was high-strung, until he came to understand what she was trying to cope with as Adam's mother.

"Now that I've been filled in by friends about how difficult her troubled son … was making things for her, I understand that it wasn't that Nancy was overwrought about the trivialities of everyday life, but that she was handling a very difficult situation with uncommon grace," he wrote in a testimonial to her on his blog.

Neighbors said the Lanzas moved several years ago into the hilly neighborhood of graceful houses and pastoral views and immediately fit into the social scene, attending the picnic after the annual Labor Day parade and a rotating ladies' night at several homes.

By the accounts of some who knew her, Nancy Lanza, who grew up in rural New Hampshire, was comfortable using guns and kept several in the house.

Landscaper Dan Holmes said Lanza often talked about her gun collection, and about taking her sons target practicing. "One thing I will note is that she was a big, big gun fan," Leff wrote on his blog.

Police have said the three weapons found near Adam Lanza's body inside the school were legally purchased and registered to his mother.

Yet it appears that Adam may have tried to buy a weapon of his own before Friday's shootings. Just days before, two federal law enforcement officials say, the 20-year-old attempted to purchase a single "long gun" rifle from a Dick's Sporting Goods store in Canton, Conn., but was turned away because he did not want to wait for a required background check.

"He didn't want to wait the 14 days," said one source, declining to be identified because the case was still under review. "The sale did not take place."

Marsha Lanza, whose husband is the brother of Adam's father, Peter Lanza, said the entire family was trying to understand what happened. She said her sister-in-law never talked of being threatened by her son, or about any violence he had committed.

"And if he did, I know she wouldn't tolerate it," she said. "If he needed help, I know they would have gotten it for him.

"Because they were the type of parents — when they were married, as well as being separated — if the kids had a need, they would definitely fulfill it."

She said Nancy Lanza divorced in 2009 and was awarded the house and enough money — up to $12,450 a month in alimony, according to local news outlets that reviewed the divorce files — that she didn't have to work.

A law enforcement source said the couple were ordered to undergo parental counseling as a condition of their divorce, but another source familiar with the case said that is a standard condition of divorces in Connecticut involving a minor child.

Other Lanza family members emerged from seclusion Saturday, and, like Marsha Lanza, expressed disbelief.

"The family of Nancy Lanza shares the grief of a community and nation as we struggle to … comprehend the loss that we all share. ... On behalf of Nancy's mother and siblings, we reach out to the community… and express our heartfelt sorrow for their incomprehensible tragedy and loss of innocence that has affected so many," the family said in a statement.

It was read at a news conference by the sheriff of Rockingham County, N.H., where Nancy Lanza's brother is employed as a law enforcement officer.

Adam Lanza's father, Peter, also issued a statement.

"Our family is grieving along with all those who have been affected by this enormous tragedy. No words can truly express how heartbroken we are," it said. "We are in a state of disbelief and trying to find whatever answers we can. We too are asking why."

molly.hennessy-fiske@latimes.com

kim.murphy@latimes.com

richard.serrano@latimes.com

Hennessy-Fiske reported from Newtown, Murphy from Seattle and Serrano from Washington, D.C.

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A children's choir opens 'SNL' with 'Silent Night'

NEW YORK (AP) — "Saturday Night Live" made a rare departure from its comedic opening to pay tribute to the children and adults killed at a Connecticut elementary school.

Not known for treating anything seriously or tenderly, the show made a fitting exception during the first moments of its show Saturday. Rather than the usual comedic sketch, a children's choir appeared on camera and angelically sang "Silent Night," with the touching refrain, "Sleep in heavenly peace."

Then the members of the New York City Children's Chorus shouted out the NBC show's time-honored introduction: "Live from New York, it's 'Saturday Night!'"

It was the night's sole reference to the tragedy and struck just the right tone.

Later, the chorus returned to join musical guest Paul McCartney in a rendition of his "Wonderful Christmas Time."

Appearing in a sketch in an unbilled cameo, actor Samuel L. Jackson made a distinctive contribution of his own.

Pretending to be miffed at getting interrupted as a guest on the mock talk show "What Up with That?" Jackson said what sounded very much like an F-bomb, followed by the term sometimes shortened to "B.S."

Playing the host of "What Up with That?" Kenan Thompson looked startled by Jackson's vulgarities but kept going.

"C'mon, Sam. That costs money!" he quipped, cracking up the studio audience.

Moments after the show ended, Jackson tried to explain in a Twitter posting.

"I only said FUH," he insisted, adding that Thompson was supposed to cut him off with his second eruption, but "blew it!!"

Jackson's tweet was accompanied by a photo of himself looking mortified.

Besides Jackson, some of the stars dropping by for this special Christmas "SNL" included Alec Baldwin, Tom Hanks, Kristen Wiig, Jimmy Fallon and Tina Fey. The guest host was Martin Short.

___

Online: www.nbc.com

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Dr. William F. House, Inventor of Cochlear Implant, Dies

Dr. William F. House, a medical researcher who braved skepticism to invent the cochlear implant, an electronic device considered to be the first to restore a human sense, died on Dec. 7 at his home in Aurora, Ore. He was 89.

The cause was metastatic melanoma, his daughter, Karen House, said.

Dr. House pushed against conventional thinking throughout his career. Over the objections of some, he introduced the surgical microscope to ear surgery. Tackling a form of vertigo that doctors had believed was psychosomatic, he developed a surgical procedure that enabled the first American in space to travel to the moon. Peering at the bones of the inner ear, he found enrapturing beauty.

Even after his ear-implant device had largely been supplanted by more sophisticated, and more expensive, devices, Dr. House remained convinced of his own version’s utility and advocated that it be used to help the world’s poor.

Today, more than 200,000 people in the world have inner-ear implants, a third of them in the United States. A majority of young deaf children receive them, and most people with the implants learn to understand speech with no visual help.

Hearing aids amplify sound to help the hearing-impaired. But many deaf people cannot hear at all because sound cannot be transmitted to their brains, however much it is amplified. This is because the delicate hair cells that line the cochlea, the liquid-filled spiral cavity of the inner ear, are damaged. When healthy, these hairs — more than 15,000 altogether — translate mechanical vibrations produced by sound into electrical signals and deliver them to the auditory nerve.

Dr. House’s cochlear implant electronically translated sound into mechanical vibrations. His initial device, implanted in 1961, was eventually rejected by the body. But after refining its materials, he created a long-lasting version and implanted it in 1969.

More than a decade would pass before the Food and Drug Administration approved the cochlear implant, but when it did, in 1984, Mark Novitch, the agency’s deputy commissioner, said, “For the first time a device can, to a degree, replace an organ of the human senses.”

One of Dr. House’s early implant patients, from an experimental trial, wrote to him in 1981 saying, “I no longer live in a world of soundless movement and voiceless faces.”

But for 27 years, Dr. House had faced stern opposition while he was developing the device. Doctors and scientists said it would not work, or not work very well, calling it a cruel hoax on people desperate to hear. Some said he was motivated by the prospect of financial gain. Some criticized him for experimenting on human subjects. Some advocates for the deaf said the device deprived its users of the dignity of their deafness without fully integrating them into the hearing world.

Even when the American Academy of Ophthalmology and Otolaryngology endorsed implants in 1977, it specifically denounced Dr. House’s version. It recommended more complicated versions, which were then under development and later became the standard.

But his work is broadly viewed as having sped the development of implants and enlarged understanding of the inner ear. Jack Urban, an aerospace engineer, helped develop the surgical microscope as well as mechanical and electronic aspects of the House implant.

Karl White, founding director of the National Center for Hearing Assessment and Management, said in an interview that it would have taken a decade longer to invent the cochlear implant without Dr. House’s contributions. He called him “a giant in the field.”

After embracing the use of the microscope in ear surgery, Dr. House developed procedures — radical for their time — for removing tumors from the back portion of the brain without causing facial paralysis; they cut the death rate from the surgery to less than 1 percent from 40 percent.

He also developed the first surgical treatment for Meniere’s disease, which involves debilitating vertigo and had been viewed as a psychosomatic condition. His procedure cured the astronaut Alan B. Shepard Jr. of the disease, clearing him to command the Apollo 14 mission to the moon in 1971. In 1961, Shepard had become the first American launched into space.

In presenting Dr. House with an award in 1995, the American Academy of Otolaryngology-Head and Neck Surgery Foundation said, “He has developed more new concepts in otology than almost any other single person in history.”

William Fouts House was born in Kansas City, Mo., on Dec. 1, 1923. When he was 3 his family moved to Whittier, Calif., where he grew up on a ranch. He did pre-dental studies at Whittier College and the University of Southern California, and earned a doctorate in dentistry at the University of California, Berkeley. After serving his required two years in the Navy — and filling the requisite 300 cavities a month — he went back to U.S.C. to pursue an interest in oral surgery. He earned his medical degree in 1953. After a residency at Los Angeles County Hospital, he joined the Los Angeles Foundation of Otology, a nonprofit research institution founded by his brother, Howard. Today it is called the House Research Institute.

Many at the time thought ear surgery was a declining field because of the effectiveness of antibiotics in dealing with ear maladies. But Dr. House saw antibiotics as enabling more sophisticated surgery by diminishing the threat of infection.

When his brother returned from West Germany with a surgical microscope, Dr. House saw its potential and adopted it for ear surgery; he is credited with introducing the device to the field. But again there was resistance. As Dr. House wrote in his memoir, “The Struggles of a Medical Innovator: Cochlear Implants and Other Ear Surgeries” (2011), some eye doctors initially criticized his use of a microscope in surgery as reckless and unnecessary for a surgeon with good eyesight.

Dr. House also used the microscope as a research tool. One night a week he would take one to a morgue for use in dissecting ears to gain insights that might lead to new surgical procedures. His initial reaction, he said, was how beautiful the bones seemed; he compared the experience to one’s first view of the Grand Canyon. His wife, the former June Stendhal, a nurse, often helped.

She died in 2008 after 64 years of marriage. In addition to his daughter, Dr. House is survived by a son, David; three grandchildren; and two great-grandchildren.

The implant Dr. House invented used a single channel to deliver information to the hearing system, as opposed to the multiple channels of competing models. The 3M Company, the original licensee of the House implant, sold its rights to another company, the Cochlear Corporation, in 1989. Cochlear later abandoned his design in favor of the multichannel version.

But Dr. House continued to fight for his single-electrode approach, saying it was far cheaper, and offered voluminous material as evidence of its efficacy. He had hoped to resume production of it and make it available to the poor around the world.

Neither the institute nor Dr. House made any money on the implant. He never sought a patent on any of his inventions, he said, because he did not want to restrict other researchers. A nephew, Dr. John House, the current president of the House institute, said his uncle had made the deal to license it to the 3M Company not for profit but simply to get it built by a reputable manufacturer.

Reflecting on his business decisions in his memoir, Dr. House acknowledged, “I might be a little richer today.”

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Don't impoverish yourself to pay kids' student loans

Dear Liz: I'm in my 50s. My kids have college loan debts that might total more than $200,000. I allowed them to take out loans because I expected to inherit $300,000 to help them pay off the debt. Now that inheritance will not happen.

I have $250,000 saved for retirement. When I'm 58 1/2 years old, I would like to pull that money out and pay some or all of these debts. Or use home equity. I've recently been downsized in employment, but I am looking to increase my income so I can help with their debt. Advice?

Answer: If your goal is to impoverish yourself so your kids will have to take care of you in your old age, by all means proceed with your plan. Otherwise, you need to rethink this.

You've been laid off in the middle of what should be your peak earning years. Older workers often have a tougher time than younger ones finding replacement jobs, even in a better economy than this one. You may not be able to replace your former income, which means you may not be able to add much to the amount you've already saved. You should be conserving your resources, including your home equity, and not squandering it repaying debts that aren't yours.

And "squandering" is the right word. You may be able to avoid paying federal and state tax penalties on withdrawals under certain conditions; distributions made after age 59 1/2 avoid the penalties, as do those made if you're "separated from service" if the job termination occurred in or after the year you turn 55. But you'll still owe income taxes on the withdrawal, and those can be considerable.

Your children are the ones who will benefit from their educations. Those educations should allow them to earn incomes to repay these loans. The amount of debt they've accrued might be excessive — you didn't specify how many kids, or whether this debt is being incurred pursuing undergraduate or graduate degrees. Ultimately, though, they will be in a better position to pay the debt than you are.

If you promised them help you can't deliver, sit down with them now to break the bad news and strategize on how they can finish their educations without incurring substantially more debt.

Your story also should serve as a cautionary tale for anyone counting on an inheritance to pay future bills. Until the money is in your bank account, it's not yours and shouldn't be part of your financial planning.

Refinancing mortgage in divorce may not be wise move

Dear Liz: My soon-to-be ex wants to refinance our mortgage to pay for renovations so we can sell it for more money. He also wants to take out some cash to pay off unsecured loans. (I have $11,000 in credit card debt, and he has over $50,000.) The house recently appraised for $310,000 and we owe $158,000 on it. Is it wise to refinance in this circumstance?

Answer: A cash-out refinance would be a risky maneuver even if you intended to stay married. Renovations rarely boost a home sale price enough to cover their cost. Also, home equity that's used to pay off credit card bills is often wasted, since the borrower never fixes the problem that led to overspending in the first place and simply runs up more debt. Since he would be getting the bulk of the benefit by having more of his debt paid off, you also would need to adjust the rest of your property settlement.

Often, the best and easiest solution in a divorce is to simply sell the house. You certainly wouldn't want to remain on a mortgage with an ex after the divorce was final, if you could possibly avoid it. A good divorce attorney can give you advice about how to proceed from here.

Make saving money automatic

Dear Liz: What's the easiest way to save money? I have the hardest time. I want to save, but I feel that I don't make enough to start saving.

Answer: The easiest way to save is to do it without thinking about it.

That usually means setting up automatic transfers either from your paycheck or from your checking account. If you have to think about putting aside money, you'll probably think of other things to do with that cash. If it's done automatically, you may be surprised at how fast the money piles up.

The second part of this equation is to leave your savings alone. If you're constantly dipping into savings to cover regular expenses, you won't get ahead.

People manage to save even on small incomes because they make it a priority. They "pay themselves first," putting aside money for savings before any other bills are paid. Start with small, regular transfers and increase them as you can.

Questions may be sent to 3940 Laurel Canyon, No. 238, Studio City, CA 91604 or by using the "Contact" form at asklizweston.com. Distributed by No More Red Inc.

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Man named in Connecticut shooting recalled as shy, awkward

Adam Lanza was memorably smart and heartbreakingly shy during his years at Newtown High School in Connecticut.

He'd correct people's Latin in ninth and 10th grades, students who knew him recall. He made the honor roll with highest honors. By his sophomore year he got into honors English, tackling "Of Mice and Men" and "Catcher in the Rye." While other youths sported T-shirts and backpacks, Lanza showed up every day in button-down shirts, carrying a briefcase.

"It was almost painful to have a conversation with him, because he felt so uncomfortable," recalls Olivia DeVivo, who sat behind him in English. "I spent so much time in my English class wondering what he was thinking."

On Friday, much of the country was engaging in the same exercise — trying to understand how Lanza, 20, could have walked into an elementary school near his home in Sandy Hook and fired a hail of bullets at terrified children and teachers, leaving 26 people dead, all but six of them children.

Police sources say the gunman shot and killed his mother at home before driving her Honda to the school, where he died of a self-inflicted gunshot wound after the rampage.

"We're looking at all the history. We're going backwards as far as we can go … and hopefully we'll stumble on some answers," said Lt. Paul Vance of the Connecticut State Police.

In interviews with neighbors and people who grew up with him, no one claimed to know the tall, gangly young man well. Family members told others he had Asperger's syndrome, a mild form of autism whose sufferers are often brilliant but socially inept.

He joined the tech club at Newtown High School, and was seen at shows and assemblies working on the sound and light equipment. But there is no record of his having finished high school.

"He was actually really smart. But I think he might have had some social disorder or something," said Hannah Basch-Gold, who went to elementary school with Lanza. "He kind of kept to himself, kind of a loner."

Fellow students said nobody made fun of Lanza; they just had a hard time connecting.

"He didn't have any friends, but he was a nice kid if you got to know him," said Kyle Kromberg, now a junior in business administration at Endicott College in Massachusetts. He studied Latin with Lanza.

"He didn't fit in with the other kids," Kromberg said. "He was very, very shy. He wouldn't look you in the eyes when he talked. He didn't really want to lock eyes with you for very long."

The Lanzas lived for many years in Sandy Hook, where neighbors said they were a quiet family that didn't attract much notice. The mother, Nancy Lanza, "was very nice. I can't say anything very bad about them," said Beth Israel, whose daughter was friends with Adam Lanza in elementary school. As for Adam, she said, "There was definitely some issues with him."

Nancy Lanza and her husband, Peter, divorced in 2008. Peter Lanza, a vice president at GE Energy Financial Services, recently remarried, and appeared to be caught off guard when reporters approached him near his home in Stamford, Conn.

"Is there something I can do for you?" he asked a reporter waiting at his house as he arrived home Friday, according to the Stamford Advocate. Told that his name had been linked to the school shooting in Newtown, his face darkened suddenly and he rolled up the window and drove into his garage.

Law enforcement sources initially identified Lanza's brother, Ryan, 24, as the shooter. Adam apparently had brother's identification with him. Ryan Lanza's photograph was distributed widely on the Internet until a post appeared on what seemed to be his Facebook page: "Everyone shut … up, it wasn't me."

Brett Wilshe, who lives near Ryan Lanza in New Jersey, said he sent his friend an instant message.

"I asked him if he was all right, and what was going on," Wilshe said. "His message back to me was it was his brother, and that was it."

Police still were trying to answer questions about how Adam Lanza got into the locked school. According to some reports, his mother was a former employee there.

A federal law enforcement source said it appeared Lanza shot himself as police arrived. The officers, he said, never had to fire their weapons. "It was over when they got there."

sam.quinones@latimes.com

kim.murphy@latimes.com

Times staff writers Matt Pearce and Richard A. Serrano contributed to this report.

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Games top App Store revenue in 2012

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School shooting postpones Cruise premiere in Pa.

NEW YORK (AP) — The U.S. premiere of the Tom Cruise action movie "Jack Reacher" is being postponed following the deadly Connecticut school shooting.

Paramount Pictures says "out of honor and respect for the families of the victims" the premiere won't take place Saturday in Pittsburgh, where "Jack Reacher" was filmed.

The premiere would've been Cruise's first U.S. media appearance since his split from Katie Holmes over the summer. It was to be more contained with select outlets covering and a location away from Hollywood or New York.

A proclamation ceremony for Cruise had been planned with Pennsylvania Gov. Tom Corbett and Pittsburgh Mayor Luke Ravenstahl.

No new date for the premiere has been set. The movie opens Dec. 21.

Friday's massacre at a Newtown, Conn., elementary school killed 20 children and several adults.

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The Neediest Cases: Disabled Young Man and His Protective Mother Deal With Life’s Challenges

Though he would prefer to put his socks on without his mother’s help, Zaquan West, 25, does not have a choice.

Michelle V. Agins/The New York Times

Joann West is a constant caretaker for her son, Zaquan. Though Ms. West works as a receptionist, the family fell behind on rent.

For the past 100 years, The New York Times Neediest Cases Fund has provided direct assistance to children, families and the elderly in New York. To celebrate the 101st campaign, an article will appear daily through Jan. 25. Each profile will illustrate the difference that even a modest amount of money can make in easing the struggles of the poor.

Last year donors contributed $7,003,854, which was distributed to those in need through seven New York charities.

2012-13 Campaign

Previously recorded:

$3,104,694

Recorded Thursday:

$137,451

*Total:

$3,242,145

Last year to date:

$2,862,836

*Includes $596,609 contributed to the Hurricane Sandy relief efforts.

The Youngest Donors

If your child or family is using creative techniques to raise money for this year’s campaign, we want to hear from you. Drop us a line on Facebook or talk to us on Twitter.

A genetic disorder has encumbered Mr. West all his life, but he has needed assistance with this particular task since only last year. In November 2011, he had surgery to remove a cancerous tumor on his left thigh that was as big as a football, but he was left less flexible.

“He doesn’t do well with disability, with the label,” his mother, Joann West, 55, said. “He doesn’t tell people that he has a disability. If they can’t see it, they just can’t see it.”

When her son was 13 months old, Ms. West learned he had neurofibromatosis, a disorder that causes tumors to grow on the nerves and, in some cases, to infringe on vital organs, or as was the case last year, to become malignant. It also creates large bumps on the skin known as nodules.

At ages 5 and 8, Zaquan had operations to remove neurofibromatosis clusters that were eating away at his left hip bone. The disease has left his left leg a few inches shorter than his right. After each operation, he had to relearn how to walk.

Because of his physical disability, he was placed in a special-education class at school and given the same homework every night, his mother said.

“I advocated for him,” Ms. West said. “I kept fighting, because he was no dummy. He was physically impaired, not mentally. I went out of my way to try to give him a better life. The system would have failed him more than it did if I hadn’t stepped in.” Her efforts led to his being moved from a special-education classroom to a regular one in second grade.

Ms. West, a single mother, acknowledges that her protective instincts made her a very controlling parent, and she did not allow Zaquan out of the house much, which limited his friendships.

“I was afraid for him,” she said. “The streets, they don’t care about your disability.”

When Mr. West entered high school, it was the first time he had truly been away from his mother’s watchful eyes. He began skipping class, often going to the park or wandering their Bedford-Stuyvesant, Brooklyn, neighborhood with truant friends. He eventually dropped out of school.

“It was just me being out on my own and making my own choices,” Mr. West recalled.

Though she did not agree with her son’s decisions, Ms. West said that his need to explore was in some ways a result of her actions. “At a point, I stepped back,” she said, “to allow him to do certain things on his own and do what he wanted to do.”

In 2007, a couple of years after he dropped out, Mr. West joined the Door, an organization focused on empowering young people to reach their potential. There, he obtained his high school equivalency diploma.

Today, Mr. West is job hunting so that he can help pay his and his mother’s expenses.

But paying the monthly bills has become a struggle, Ms. West said, in part because of a recent change in her budget. In August, after an increase in income, they stopped receiving $324 a month in food stamps. The additional income did not cover all their expenses, however, and Ms. West eventually fell behind in the rent on their apartment.

Ms. West, who has been employed in various administrative jobs, currently works as a receptionist for Howie the Harp Advocacy Center, an agency that provides employment help to people with psychiatric disabilities. Her annual salary is about $25,000 before taxes. Her son receives $646 in Social Security disability benefits. After the family’s food stamps were cut off, Mr. West applied individually, and he now receives $200 in food stamps each month.

With the addition of Mr. West’s disability benefits and food stamps, their net monthly income is $2,213. Their contribution for the Section 8-subsidized apartment Ms. West has lived in for the past 30 years is $969.

Knowing she was in need of help, Ms. West’s boss told her about the Community Service Society, one of the organizations supported by The New York Times Neediest Cases Fund. And the society drew $1,598 from the fund to cover her debt.

Ms. West remains a constant caretaker for her independent-minded son, who, she says, has come to accept her help grudgingly. She says that even if they are not on speaking terms after a disagreement, she is there to lend him a hand.

Both are continuing to deal with the inevitable challenges: Mr. West is awaiting word from doctors on whether a new growth in his lungs is cancerous. But one of his greatest assets, given all that he has overcome, is that he is comfortable in his own skin.

“I’m just always going to be me,” he said, “so why deal with somebody else?”

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